5ET4

Structure of RNase A-K7H/R10H in complex with 3'-CMP

5ET4 の概要

• エントリーDOI: 10.2210/pdb5et4/pdb
• 関連するPDBエントリー: 4U7R
• 分子名称: Ribonuclease pancreatic, CYTIDINE-3'-MONOPHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• 機能のキーワード: rnase a, p2 subsite, exonuclease activity, hydrolase
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56203.95

構造登録者

Blanco, J.A.,Salazar, V.A.,Moussaoui, M.,Boix, E. (登録日: 2015-11-17, 公開日: 2016-11-30, 最終更新日: 2024-01-10)

• 主引用文献: Prats-Ejarque, G.,Blanco, J.A.,Salazar, V.A.,Nogues, V.M.,Moussaoui, M.,Boix, E.; Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.; Biochim Biophys Acta Gen Subj, 1863:105-117, 2019; PubMed: 30287244; DOI: 10.1016/j.bbagen.2018.09.021

実験手法

X-RAY DIFFRACTION (2.1 Å)