5EP2

Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor

5EP2 の概要

• エントリーDOI: 10.2210/pdb5ep2/pdb
• 関連するPDBエントリー: 5EP0 5EP1 5EP3 5EP4
• 分子名称: Putative repressor protein luxO, 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: quorum sensing, aaa+ protein, catalytic domain, atpase, inhibitor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• 由来する生物種: Photobacterium angustum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29063.11

構造登録者

Shah, T.,Selcuk, H.B.,Jeffrey, P.D.,Hughson, F.M. (登録日: 2015-11-11, 公開日: 2016-04-20, 最終更新日: 2024-03-06)

• 主引用文献: Boyaci, H.,Shah, T.,Hurley, A.,Kokona, B.,Li, Z.,Ventocilla, C.,Jeffrey, P.D.,Semmelhack, M.F.,Fairman, R.,Bassler, B.L.,Hughson, F.M.; Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.; Plos Biol., 14:e1002464-e1002464, 2016; PubMed: 27219477; DOI: 10.1371/journal.pbio.1002464

実験手法

X-RAY DIFFRACTION (1.421 Å)