5ELI

Triggering receptor expressed on myeloid cells 2

5ELI の概要

• エントリーDOI: 10.2210/pdb5eli/pdb
• 分子名称: Triggering receptor expressed on myeloid cells 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• 機能のキーワード: activating receptors, trem2, innate immunity, immune system receptor, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28740.40

構造登録者

Brett, T.J.,Kober, D.L. (登録日: 2015-11-04, 公開日: 2016-12-28, 最終更新日: 2023-09-27)

• 主引用文献: Kober, D.L.,Alexander-Brett, J.M.,Karch, C.M.,Cruchaga, C.,Colonna, M.,Holtzman, M.J.,Brett, T.J.; Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.; Elife, 5:-, 2016; PubMed: 27995897; DOI: 10.7554/eLife.20391

実験手法

X-RAY DIFFRACTION (3.0977 Å)