5EKF
Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1
Summary for 5EKF
Entry DOI | 10.2210/pdb5ekf/pdb |
Related | 5EKG |
Descriptor | DNA repair protein complementing XP-G cells, Importin subunit alpha-1 (3 entities in total) |
Functional Keywords | importin alpha, nuclear import pathway, nuclear localization sequence (nls), dna repair proteins, nucleotide excision repair, xpg protein, protein binding |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus : P28715 Cytoplasm : P52293 |
Total number of polymer chains | 3 |
Total formula weight | 60896.90 |
Authors | Barros, A.C.,Takeda, A.A.S.,Fontes, M.R.M. (deposition date: 2015-11-03, release date: 2016-02-10, Last modification date: 2024-03-06) |
Primary citation | Barros, A.C.,Takeda, A.A.,Dreyer, T.R.,Velazquez-Campoy, A.,Kobe, B.,Fontes, M.R. Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428:2120-2131, 2016 Cited by PubMed: 26812207DOI: 10.1016/j.jmb.2016.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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