5EFX

Crystal structure of Rho GTPase regulator

Summary for 5EFX

Entry DOI	10.2210/pdb5efx/pdb
Descriptor	Rho guanine nucleotide exchange factor 2 (2 entities in total)
Functional Keywords	rho gtpase, activity, signaling protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: Q92974
Total number of polymer chains	1
Total formula weight	16604.27
Authors	Jiang, Y.,Ouyang, S.,Liu, Z.J. (deposition date: 2015-10-26, release date: 2016-06-29, Last modification date: 2023-11-08)
Primary citation	Jiang, Y.,Jiang, H.,Zhou, S.,Meng, B.,Liu, Z.J.,Ouyang, S. Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding Biochem.Biophys.Res.Commun., 471:621-627, 2016 Cited by PubMed: 26820534 DOI: 10.1016/j.bbrc.2016.01.150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.451 Å)

Structure validation