5EEH
Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 2-chloro-4-nitrophenol
Summary for 5EEH
Entry DOI | 10.2210/pdb5eeh/pdb |
Related | 5EEG |
Descriptor | Carminomycin 4-O-methyltransferase DnrK, S-ADENOSYL-L-HOMOCYSTEINE, 2-chloranyl-4-nitro-phenol, ... (5 entities in total) |
Functional Keywords | unnatural substrate, structural genomics, psi-biology, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, transferase |
Biological source | Streptomyces peucetius |
Total number of polymer chains | 3 |
Total formula weight | 127622.33 |
Authors | Wang, F.,Singh, S.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2015-10-22, release date: 2015-12-16, Last modification date: 2023-09-27) |
Primary citation | Huber, T.D.,Wang, F.,Singh, S.,Johnson, B.R.,Zhang, J.,Sunkara, M.,Van Lanen, S.G.,Morris, A.J.,Phillips, G.N.,Thorson, J.S. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. Acs Chem.Biol., 11:2484-2491, 2016 Cited by PubMed: 27351335DOI: 10.1021/acschembio.6b00348 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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