5ED3
crystal structure of human Hint1 complexing with AP5A
Summary for 5ED3
Entry DOI | 10.2210/pdb5ed3/pdb |
Related | 5ECB 5ECZ 5ED5 5ED6 5EDE 5EFL 5EFP |
Descriptor | Histidine triad nucleotide-binding protein 1, ADENOSINE MONOPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | hydrolase, nucleotide binding, regulation of transcription, signal transduction |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 28633.86 |
Authors | |
Primary citation | Yu, J.,Liu, Z.,Liang, Y.,Luo, F.,Zhang, J.,Tian, C.,Motzik, A.,Zheng, M.,Kang, J.,Zhong, G.,Liu, C.,Fang, P.,Guo, M.,Razin, E.,Wang, J. Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10:4664-4664, 2019 Cited by PubMed: 31604935DOI: 10.1038/s41467-019-12710-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.309 Å) |
Structure validation
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