5EAJ

Crystal structure of DHFR in 0% Isopropanol

Summary for 5EAJ

• Entry DOI: 10.2210/pdb5eaj/pdb
• Related: 5E8Q
• Descriptor: Dihydrofolate reductase, FOLIC ACID, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: dynamics, oxidoreductase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 37105.34

Authors

Cuneo, M.J.,Agarwal, P.K. (deposition date: 2015-10-16, release date: 2016-09-21, Last modification date: 2023-09-27)

• Primary citation: Duff Jr., M.R.,Borreguero, J.M.,Cuneo, M.J.,Ramanathan, A.,He, J.,Kamath, G.,Chennubhotla, S.C.,Meilleur, F.,Howell, E.E.,Herwig, K.W.,Myles, D.A.A.,Agarwal, P.K.; Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.; Biochemistry, 57:4263-4275, 2018; PubMed: 29901984; DOI: 10.1021/acs.biochem.8b00424

Experimental method

X-RAY DIFFRACTION (1.701 Å)