5EAD

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor S-desthio-prothioconazole

5EAD の概要

• エントリーDOI: 10.2210/pdb5ead/pdb
• 関連するPDBエントリー: 4WMZ 5EAB 5EAC 5EAE 5EAF 5EAG 5EAH
• 分子名称: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, (2~{S})-2-(1-chloranylcyclopropyl)-1-(2-chlorophenyl)-3-(1,2,4-triazol-1-yl)propan-2-ol, ... (4 entities in total)
• 機能のキーワード: cyp51, s-desthio-prothioconazole, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase-oxidoreducatse inhibitor complex, oxidoreductase/oxidoreducatse inhibitor
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62813.90

構造登録者

Tyndall, J.D.A.,Sabherwal, M.,Sagatova, A.A.,Keniya, M.V.,Wilson, R.K.,Woods, M.V.,Monk, B.C. (登録日: 2015-10-16, 公開日: 2016-02-10, 最終更新日: 2023-09-27)

• 主引用文献: Tyndall, J.D.,Sabherwal, M.,Sagatova, A.A.,Keniya, M.V.,Negroni, J.,Wilson, R.K.,Woods, M.A.,Tietjen, K.,Monk, B.C.; Structural and Functional Elucidation of Yeast Lanosterol 14 alpha-Demethylase in Complex with Agrochemical Antifungals.; PLoS ONE, 11:e0167485-e0167485, 2016; PubMed: 27907120; DOI: 10.1371/journal.pone.0167485

実験手法

X-RAY DIFFRACTION (2 Å)