5E9E

Crystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with AMP-PNP

Summary for 5E9E

• Entry DOI: 10.2210/pdb5e9e/pdb
• Related: 3LKM 3LLA 3LMH 3LMI 3PDT 4ZME 4ZMF 4ZS4 5E4H
• Descriptor: Myosin-II heavy chain kinase A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION, ... (5 entities in total)
• Functional Keywords: atypical ser/thr protein kinase, alpha kinase, transferase
• Biological source: Dictyostelium discoideum (Slime mold)
• Total number of polymer chains: 2
• Total formula weight: 70386.32

Authors

Ye, Q.,Jia, Z. (deposition date: 2015-10-15, release date: 2016-06-08, Last modification date: 2023-09-27)

• Primary citation: Ye, Q.,Yang, Y.,van Staalduinen, L.,Crawley, S.W.,Liu, L.,Brennan, S.,Cote, G.P.,Jia, Z.; Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.; Sci Rep, 6:26634-26634, 2016; PubMed: 27211275; DOI: 10.1038/srep26634

Experimental method

X-RAY DIFFRACTION (2.4 Å)