5E94
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
Summary for 5E94
Entry DOI | 10.2210/pdb5e94/pdb |
Descriptor | Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, Glucagon-like peptide 1 receptor, ... (4 entities in total) |
Functional Keywords | antibody antagonist glp-1 receptor, immune system, membrane protein |
Biological source | Mus musculus (House Mouse) More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P43220 |
Total number of polymer chains | 6 |
Total formula weight | 125380.77 |
Authors | Soroka, V.,Schluckebier, G.,Reedtz-Runge, S. (deposition date: 2015-10-14, release date: 2016-08-24, Last modification date: 2024-01-10) |
Primary citation | Hennen, S.,Kodra, J.T.,Soroka, V.,Krogh, B.O.,Wu, X.,Kaastrup, P.,Orskov, C.,Ronn, S.G.,Schluckebier, G.,Barbateskovic, S.,Gandhi, P.S.,Reedtz-Runge, S. Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor. Sci Rep, 6:26236-26236, 2016 Cited by PubMed: 27196125DOI: 10.1038/srep26236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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