5E94

Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain

5E94 の概要

• エントリーDOI: 10.2210/pdb5e94/pdb
• 分子名称: Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, Glucagon-like peptide 1 receptor, ... (4 entities in total)
• 機能のキーワード: antibody antagonist glp-1 receptor, immune system, membrane protein
• 由来する生物種: Mus musculus (House Mouse); 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P43220
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 125380.77

構造登録者

Soroka, V.,Schluckebier, G.,Reedtz-Runge, S. (登録日: 2015-10-14, 公開日: 2016-08-24, 最終更新日: 2024-01-10)

• 主引用文献: Hennen, S.,Kodra, J.T.,Soroka, V.,Krogh, B.O.,Wu, X.,Kaastrup, P.,Orskov, C.,Ronn, S.G.,Schluckebier, G.,Barbateskovic, S.,Gandhi, P.S.,Reedtz-Runge, S.; Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.; Sci Rep, 6:26236-26236, 2016; PubMed: 27196125; DOI: 10.1038/srep26236

実験手法

X-RAY DIFFRACTION (2 Å)