5E6V

Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit

5E6V の概要

• エントリーDOI: 10.2210/pdb5e6v/pdb
• 分子名称: Integrin beta-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: lymphocyte function-associated antigen-1, lfa-1, cell adhesion
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25968.20

構造登録者

Sen, M.,Springer, T.A. (登録日: 2015-10-10, 公開日: 2016-03-02, 最終更新日: 2020-07-29)

• 主引用文献: Sen, M.,Springer, T.A.; Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.; Proc.Natl.Acad.Sci.USA, 113:2940-2945, 2016; PubMed: 26936951; DOI: 10.1073/pnas.1601379113

実験手法

X-RAY DIFFRACTION (1.8 Å)