5E5V

Structure of amyloid forming peptide NFGAILS (residues 22-28) from Islet Amyloid Polypeptide

Summary for 5E5V

Entry DOI	10.2210/pdb5e5v/pdb
Related	5E5X 5E5Z 5E61
Descriptor	NFGAILS (22-28) from islet amyloid polypeptide, synthesized (2 entities in total)
Functional Keywords	amyloid-like protofibril, protein fibril, de novo protein, membrane protein
Biological source	Homo sapiens
Total number of polymer chains	2
Total formula weight	1441.63
Authors	Soriaga, A.B.,Macdonald, R.,Sawaya, M.R.,Sangwan, S.,Eisenberg, D. (deposition date: 2015-10-09, release date: 2015-12-16, Last modification date: 2024-03-06)
Primary citation	Soriaga, A.B.,Sangwan, S.,Macdonald, R.,Sawaya, M.R.,Eisenberg, D. Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. J.Phys.Chem.B, 120:5810-5816, 2016 Cited by PubMed: 26629790 DOI: 10.1021/acs.jpcb.5b09981 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation