5E41
Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentenyl)-2'-deoxyuridine-triphosphate
Summary for 5E41
Entry DOI | 10.2210/pdb5e41/pdb |
Descriptor | DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (7 entities in total) |
Functional Keywords | linker-modified nucleotide, klentaq, dna polymerase, transferase |
Biological source | Thermus aquaticus More |
Total number of polymer chains | 3 |
Total formula weight | 70641.06 |
Authors | Hottin, A.,Betz, K.,Marx, A. (deposition date: 2015-10-05, release date: 2016-12-07, Last modification date: 2024-01-10) |
Primary citation | Hottin, A.,Betz, K.,Diederichs, K.,Marx, A. Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides. Chemistry, 23:2109-2118, 2017 Cited by PubMed: 27901305DOI: 10.1002/chem.201604515 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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