5E2V
Anti-TAU AT8 FAB with doubly phosphorylated TAU peptide
Summary for 5E2V
Entry DOI | 10.2210/pdb5e2v/pdb |
Related | 5E2T 5E2U 5E2W |
Descriptor | AT8 LIGHT CHAIN, AT8 HEAVY CHAIN, TAU PHOSPHOPEPTIDE, ... (5 entities in total) |
Functional Keywords | immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 50271.70 |
Authors | Malia, T.,Teplyakov, A. (deposition date: 2015-10-01, release date: 2016-02-24, Last modification date: 2023-09-27) |
Primary citation | Malia, T.J.,Teplyakov, A.,Ernst, R.,Wu, S.J.,Lacy, E.R.,Liu, X.,Vandermeeren, M.,Mercken, M.,Luo, J.,Sweet, R.W.,Gilliland, G.L. Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8. Proteins, 84:427-434, 2016 Cited by PubMed: 26800003DOI: 10.1002/prot.24988 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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