5E18

T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)

5E18 の概要

• エントリーDOI: 10.2210/pdb5e18/pdb
• 関連するPDBエントリー: 5E17
• 分子名称: DNA-directed RNA polymerase subunit alpha, ZINC ION, DNA-directed RNA polymerase subunit beta, ... (11 entities in total)
• 機能のキーワード: dna, single-stranded, dna-directed rna polymerases, gene expression regulation, bacterial, promoter regions, protein conformation, sigma factor, thermus thermophilus, transcription initiation, discriminator, consensus, rna, abortive, sigma, transcription start site, scrunching, transcription-dna-rna complex, transcription/dna/rna
• 由来する生物種: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); 詳細
• 細胞内の位置: Cytoplasm : Q5SKW1
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 446344.09

構造登録者

Zhang, Y.,Ebright, R.H. (登録日: 2015-09-29, 公開日: 2016-03-09, 最終更新日: 2023-09-27)

• 主引用文献: Winkelman, J.T.,Vvedenskaya, I.O.,Zhang, Y.,Zhang, Y.,Bird, J.G.,Taylor, D.M.,Gourse, R.L.,Ebright, R.H.,Nickels, B.E.; Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.; Science, 351:1090-1093, 2016; PubMed: 26941320; DOI: 10.1126/science.aad6881

実験手法

X-RAY DIFFRACTION (3.3 Å)