5E0E
Crystal Structure of Cytochrome P450 2B37 from Desert Woodrat in complex with 4-(4-chlorophenyl)imidazole
Summary for 5E0E
Entry DOI | 10.2210/pdb5e0e/pdb |
Descriptor | Cytochrome P450 family 2 subfamily B, PROTOPORPHYRIN IX CONTAINING FE, 4-(4-CHLOROPHENYL)IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | cytochrome p450, cyp2b37, 4-(4-chlorophenyl)imidazole, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Neotoma lepida (Desert woodrat) |
Total number of polymer chains | 1 |
Total formula weight | 54351.20 |
Authors | Shah, M.B.,Halpert, J.R.,Stout, C.D. (deposition date: 2015-09-28, release date: 2016-02-10, Last modification date: 2023-09-27) |
Primary citation | Shah, M.B.,Liu, J.,Huo, L.,Zhang, Q.,Dearing, M.D.,Wilderman, P.R.,Szklarz, G.D.,Stout, C.D.,Halpert, J.R. Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Mol.Pharmacol., 89:435-445, 2016 Cited by PubMed: 26826176DOI: 10.1124/mol.115.102111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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