5DZC
Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - AMPPNP bound
Summary for 5DZC
Entry DOI | 10.2210/pdb5dzc/pdb |
Related | 4MYI 4WJC |
Descriptor | cGMP-dependent protein kinase, putative, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UNKNOWN ATOM OR ION, ... (6 entities in total) |
Functional Keywords | structural genomics consortium (sgc), kinase, transferase |
Biological source | Plasmodium vivax (strain Salvador I) |
Total number of polymer chains | 1 |
Total formula weight | 97362.19 |
Authors | Walker, J.R.,El Bakkouri, M.,Loppnau, P.,Graslund, S.,He, H.,Seitova, A.,Hutchinson, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,Amani, M.,Structural Genomics Consortium (SGC) (deposition date: 2015-09-25, release date: 2015-10-14, Last modification date: 2023-09-27) |
Primary citation | El Bakkouri, M.,Kouidmi, I.,Wernimont, A.K.,Amani, M.,Hutchinson, A.,Loppnau, P.,Kim, J.J.,Flueck, C.,Walker, J.R.,Seitova, A.,Senisterra, G.,Kakihara, Y.,Kim, C.,Blackman, M.J.,Calmettes, C.,Baker, D.A.,Hui, R. Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proc.Natl.Acad.Sci.USA, 116:14164-14173, 2019 Cited by PubMed: 31239348DOI: 10.1073/pnas.1905558116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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