5DZ5
Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P41212 space group
Summary for 5DZ5
Entry DOI | 10.2210/pdb5dz5/pdb |
Related | 5DO6 5DU1 |
Descriptor | Mambalgin-1 (2 entities in total) |
Functional Keywords | pain-relieving polypeptide, analgesic, acid-sensing ion channel, mambalgin-1, three-finger-fold, toxin |
Biological source | Dendroaspis polylepis polylepis (Black mamba) |
Cellular location | Secreted : P0DKR6 |
Total number of polymer chains | 2 |
Total formula weight | 13149.29 |
Authors | Stura, E.A.,Tepshi, L.,Mourier, G.,Kessler, P.,Servent, D. (deposition date: 2015-09-25, release date: 2015-12-30, Last modification date: 2024-01-10) |
Primary citation | Mourier, G.,Salinas, M.,Kessler, P.,Stura, E.A.,Leblanc, M.,Tepshi, L.,Besson, T.,Diochot, S.,Baron, A.,Douguet, D.,Lingueglia, E.,Servent, D. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291:2616-2629, 2016 Cited by PubMed: 26680001DOI: 10.1074/jbc.M115.702373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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