5DW3
Tryptophan Synthase beta-subunit from Pyrococcus furiosus with product L-tryptophan non-covalently bound in the active site
Summary for 5DW3
| Entry DOI | 10.2210/pdb5dw3/pdb |
| Related | 5DVZ 5DW0 5E0K |
| Descriptor | Tryptophan synthase beta chain 1, SODIUM ION, TRYPTOPHAN, ... (5 entities in total) |
| Functional Keywords | tryptophan synthase, plp, external aldimine, substrate bound, lyase |
| Biological source | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
| Total number of polymer chains | 4 |
| Total formula weight | 176638.99 |
| Authors | Buller, A.R.,Arnold, F.H. (deposition date: 2015-09-22, release date: 2015-11-11, Last modification date: 2019-12-25) |
| Primary citation | Buller, A.R.,Brinkmann-Chen, S.,Romney, D.K.,Herger, M.,Murciano-Calles, J.,Arnold, F.H. Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112:14599-14604, 2015 Cited by PubMed: 26553994DOI: 10.1073/pnas.1516401112 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
Download full validation report
