5DVZ

Holo TrpB from Pyrococcus furiosus

Summary for 5DVZ

Entry DOI	10.2210/pdb5dvz/pdb
Related	5DW0 5DW3
Descriptor	Tryptophan synthase beta chain 1, SODIUM ION, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	type ii plp enzyme, tryptophan biosynthesis, ec 4.2.1.20, lyase
Biological source	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Total number of polymer chains	4
Total formula weight	176012.03
Authors	Buller, A.R.,Arnold, F.H. (deposition date: 2015-09-21, release date: 2016-02-03, Last modification date: 2019-12-25)
Primary citation	Buller, A.R.,Brinkmann-Chen, S.,Romney, D.K.,Herger, M.,Murciano-Calles, J.,Arnold, F.H. Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112:14599-14604, 2015 Cited by PubMed: 26553994 DOI: 10.1073/pnas.1516401112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation