5DV4

Crystal structure of human CNOT6L in complex with neomycin

Summary for 5DV4

Related5DV2
DescriptorCCR4-NOT transcription complex subunit 6-like, NEOMYCIN, SULFATE ION, ... (4 entities in total)
Functional Keywordsnuclease domain, deadenylase, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm Q96LI5
Total number of polymer chains1
Total molecular weight45947.27
Authors
Zhang, Q.,Bartlam, M. (deposition date: 2015-09-21, release date: 2016-10-26)
Primary citation
Zhang, Q.,Yan, D.,Guo, E.,Ding, B.,Yang, W.,Liu, R.,Yamamoto, T.,Bartlam, M.
Structural basis for inhibition of the deadenylase activity of human CNOT6L
Febs Lett., 590:1270-1279, 2016
PubMed: 27013054 (PDB entries with the same primary citation)
DOI: 10.1002/1873-3468.12160
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.221120.6%0.6%9.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution