5DTP
Crystal structure of M. tuberculosis EchA6 (apo, trigonal crystal form)
Summary for 5DTP
Entry DOI | 10.2210/pdb5dtp/pdb |
Descriptor | Probable enoyl-CoA hydratase echA6 (2 entities in total) |
Functional Keywords | enoyl-coa hydratase-like, lyase, lipid binding protein |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 3 |
Total formula weight | 84489.35 |
Authors | Cox, J.A.G.,Besra, G.S.,Futterer, K. (deposition date: 2015-09-18, release date: 2016-01-20, Last modification date: 2024-01-10) |
Primary citation | Cox, J.A.,Abrahams, K.A.,Alemparte, C.,Ghidelli-Disse, S.,Rullas, J.,Angulo-Barturen, I.,Singh, A.,Gurcha, S.S.,Nataraj, V.,Bethell, S.,Remuinan, M.J.,Encinas, L.,Jervis, P.J.,Cammack, N.C.,Bhatt, A.,Kruse, U.,Bantscheff, M.,Futterer, K.,Barros, D.,Ballell, L.,Drewes, G.,Besra, G.S. THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol, 1:15006-15006, 2016 Cited by PubMed: 27571973DOI: 10.1038/nmicrobiol.2015.6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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