5DSC

Context-independent anti-hypusine antibody FabHpu24.B in complex with hypusine

Summary for 5DSC

• Entry DOI: 10.2210/pdb5dsc/pdb
• Related: 5DRN 5DS8 5DTF 5DUB
• Descriptor: Fab Hpu24.B Heavy Chain, Fab Hou24.B Light Chain, Peptide: GLY-HPU-GLY-SER-GLY, ... (4 entities in total)
• Functional Keywords: hypusine, antibody, fabhpu24.b, eif5a, immune system
• Biological source: Oryctolagus cuniculus; More
• Total number of polymer chains: 12
• Total formula weight: 188081.86

Authors

Zhai, Q.,Carter, P.J. (deposition date: 2015-09-17, release date: 2016-01-20, Last modification date: 2023-11-15)

• Primary citation: Zhai, Q.,He, M.,Song, A.,Deshayes, K.,Dixit, V.M.,Carter, P.J.; Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.; J.Mol.Biol., 428:603-617, 2016; PubMed: 26778617; DOI: 10.1016/j.jmb.2016.01.006

Experimental method

X-RAY DIFFRACTION (2.4 Å)