5DS8

Context-independent anti-hypusine antibody FabHpu98 in complex with hypusine

Summary for 5DS8

• Entry DOI: 10.2210/pdb5ds8/pdb
• Related: 5DRN 5DSC 5DTF 5DUB
• Descriptor: Fab Hpu98 Heavy Chain, Fab Hou98 Light Chain, Tetrapeptide GLY-HPU-GLY-ALA, ... (6 entities in total)
• Functional Keywords: hypusine, antibody, fabhpu98, eif5a, immune system
• Biological source: Oryctolagus cuniculus; More
• Total number of polymer chains: 5
• Total formula weight: 93999.82

Authors

Zhai, Q.,Carter, P.J. (deposition date: 2015-09-17, release date: 2016-01-20, Last modification date: 2023-11-15)

• Primary citation: Zhai, Q.,He, M.,Song, A.,Deshayes, K.,Dixit, V.M.,Carter, P.J.; Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.; J.Mol.Biol., 428:603-617, 2016; PubMed: 26778617; DOI: 10.1016/j.jmb.2016.01.006

Experimental method

X-RAY DIFFRACTION (1.95 Å)