5DS6

Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA with splayed ends

5DS6 の概要

• エントリーDOI: 10.2210/pdb5ds6/pdb
• 関連するPDBエントリー: 4P6I
• 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (29-MER), ... (4 entities in total)
• 機能のキーワード: adaptive immunity, crispr-associated proteins, crispr-cas systems, clustered regularly interspaced short palindromic repeats, integrases, endodeoxyribonucleases, endonucleases, dna binding protein, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 176907.00

構造登録者

Nunez, J.K.,Harrington, L.B.,Kranzusch, P.J.,Engelman, A.N.,Doudna, J.A. (登録日: 2015-09-16, 公開日: 2015-10-28, 最終更新日: 2023-09-27)

• 主引用文献: Nunez, J.K.,Harrington, L.B.,Kranzusch, P.J.,Engelman, A.N.,Doudna, J.A.; Foreign DNA capture during CRISPR-Cas adaptive immunity.; Nature, 527:535-538, 2015; PubMed: 26503043; DOI: 10.1038/nature15760

実験手法

X-RAY DIFFRACTION (3.352 Å)