5DO2

Complex structure of MERS-RBD bound with 4C2 antibody

Summary for 5DO2

Related4KR0
DescriptorS protein, 4C2 heavy chain, 4C2 light chain, ... (5 entities in total)
Functional Keywordsreceptor-binding domain of mers-cov spike, 4c2 antibody, neuralization, receptor-binding blocking., viral protein-immune system complex, viral protein/immune system
Biological sourceMiddle East respiratory syndrome coronavirus
More
Total number of polymer chains6
Total molecular weight149787.68
Authors
Li, Y.,Wan, Y.,Liu, P.,Zhao, J.,Lu, G.,Qi, J.,Wang, Q.,Lu, X.,Wu, Y.,Liu, W.,Yuen, K.Y.,Perlman, S.,Gao, G.F.,Yan, J. (deposition date: 2015-09-10, release date: 2015-10-14, Last modification date: 2015-11-11)
Primary citation
Li, Y.,Wan, Y.,Liu, P.,Zhao, J.,Lu, G.,Qi, J.,Wang, Q.,Lu, X.,Wu, Y.,Liu, W.,Zhang, B.,Yuen, K.Y.,Perlman, S.,Gao, G.F.,Yan, J.
A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25:1237-1249, 2015
PubMed: 26391698 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2015.113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.409 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.290130.8%5.2%15.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution