5DG0
Human APE1 phosphorothioate substrate complex with Mn2+
Summary for 5DG0
Entry DOI | 10.2210/pdb5dg0/pdb |
Descriptor | DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(OMC)P*(48Z)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (7 entities in total) |
Functional Keywords | hydrolase and lyase - dna complex, hydrolase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 75968.73 |
Authors | Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-08-27, release date: 2015-10-14, Last modification date: 2023-09-27) |
Primary citation | Freudenthal, B.D.,Beard, W.A.,Cuneo, M.J.,Dyrkheeva, N.S.,Wilson, S.H. Capturing snapshots of APE1 processing DNA damage. Nat.Struct.Mol.Biol., 22:924-931, 2015 Cited by PubMed: 26458045DOI: 10.1038/nsmb.3105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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