5DF8

CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CEFOPERAZONE

5DF8 の概要

• エントリーDOI: 10.2210/pdb5df8/pdb
• 関連するPDBエントリー: 5DF7
• 分子名称: Cell division protein, (2R,4R,5R)-2-[(1R)-1-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5-methyl-1,3-thiazinane-4-carboxylic acid, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: cefoperazone, beta-lactam antibiotics, acyl-enzyme complex, de-acylation, transferase
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124141.60

構造登録者

Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J. (登録日: 2015-08-26, 公開日: 2016-01-13)

• 主引用文献: Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J.; Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.; Febs Lett., 590:288-297, 2016; PubMed: 26823174; DOI: 10.1002/1873-3468.12054

実験手法

X-RAY DIFFRACTION (2 Å)