5DBG

Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NAD+

Summary for 5DBG

• Entry DOI: 10.2210/pdb5dbg/pdb
• Related: 5DBF 5DBI
• Descriptor: Iridoid synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: metal-binding, substrate binding, acidocalcisomal pyrophosphatase, inhibitor, oxidoreductase
• Biological source: Catharanthus roseus (Madagascar periwinkle)
• Cellular location: Cytoplasm, cytosol : K7WDL7
• Total number of polymer chains: 2
• Total formula weight: 85893.69

Authors

Liu, W.D.,Hu, Y.M.,Zheng, Y.Y.,Xu, Z.X.,Ko, T.P.,Chen, C.C.,Guo, R.T. (deposition date: 2015-08-21, release date: 2015-11-04, Last modification date: 2023-11-08)

• Primary citation: Hu, Y.M.,Liu, W.D.,Malwal, S.R.,Zheng, Y.Y.,Feng, X.X.,Ko, T.P.,Chen, C.C.,Xu, Z.X.,Liu, M.X.,Han, X.,Gao, J.,Oldfield, E.,Guo, R.T.; Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms; Angew.Chem.Int.Ed.Engl., 54:15478-15482, 2015; PubMed: 26768532; DOI: 10.1002/anie.201508310

Experimental method

X-RAY DIFFRACTION (1.95 Å)