Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5DB0

Menin in complex with MI-352

Summary for 5DB0
Entry DOI10.2210/pdb5db0/pdb
Related5DB1 5DB2 5DB3
DescriptorMenin, TETRAETHYLENE GLYCOL, SULFATE ION, ... (7 entities in total)
Functional Keywordsprotein binding, protein binding-inhibitor complex, protein binding/inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight56938.87
Authors
Pollock, J.,Dmitry, B.,Cierpicki, T.,Grembecka, J. (deposition date: 2015-08-20, release date: 2016-03-30, Last modification date: 2023-09-27)
Primary citationBorkin, D.,Pollock, J.,Kempinska, K.,Purohit, T.,Li, X.,Wen, B.,Zhao, T.,Miao, H.,Shukla, S.,He, M.,Sun, D.,Cierpicki, T.,Grembecka, J.
Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL).
J.Med.Chem., 59:892-913, 2016
Cited by
PubMed: 26744767
DOI: 10.1021/acs.jmedchem.5b01305
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon