5D96

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1

5D96 の概要

• エントリーDOI: 10.2210/pdb5d96/pdb
• 関連するPDBエントリー: 4IJ3 5DI8
• 分子名称: Sulfhydryl oxidase 1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, ... (4 entities in total)
• 機能のキーワード: enzyme, inhibitor, antibody, dual-specificity, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Isoform 1: Golgi apparatus membrane ; Single-pass membrane protein . Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted: Q8BND5
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 148018.05

構造登録者

Fass, D.,Grossman, I. (登録日: 2015-08-18, 公開日: 2016-02-10, 最終更新日: 2024-01-10)

• 主引用文献: Grossman, I.,Ilani, T.,Fleishman, S.J.,Fass, D.; Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.; Protein Eng.Des.Sel., 29:135-147, 2016; PubMed: 26819240; DOI: 10.1093/protein/gzv067

実験手法

X-RAY DIFFRACTION (2.3 Å)