5D93
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
Summary for 5D93
Entry DOI | 10.2210/pdb5d93/pdb |
Related | 5D8I |
Descriptor | Sulfhydryl oxidase 1, Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, ... (4 entities in total) |
Functional Keywords | enzyme, inhibitor, thioredoxin fold, antibody, oxidoreductase |
Biological source | Mus musculus (Mouse) More |
Cellular location | Isoform 1: Golgi apparatus membrane ; Single-pass membrane protein . Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted: Q8BND5 |
Total number of polymer chains | 6 |
Total formula weight | 147248.70 |
Authors | Grossman, I.,Fass, D. (deposition date: 2015-08-18, release date: 2016-02-10, Last modification date: 2024-01-10) |
Primary citation | Grossman, I.,Ilani, T.,Fleishman, S.J.,Fass, D. Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma. Protein Eng.Des.Sel., 29:135-147, 2016 Cited by PubMed: 26819240DOI: 10.1093/protein/gzv067 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.201 Å) |
Structure validation
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