5D93

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody

5D93 の概要

• エントリーDOI: 10.2210/pdb5d93/pdb
• 関連するPDBエントリー: 5D8I
• 分子名称: Sulfhydryl oxidase 1, Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, ... (4 entities in total)
• 機能のキーワード: enzyme, inhibitor, thioredoxin fold, antibody, oxidoreductase
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Isoform 1: Golgi apparatus membrane ; Single-pass membrane protein . Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted: Q8BND5
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 147248.70

構造登録者

Grossman, I.,Fass, D. (登録日: 2015-08-18, 公開日: 2016-02-10, 最終更新日: 2024-01-10)

• 主引用文献: Grossman, I.,Ilani, T.,Fleishman, S.J.,Fass, D.; Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.; Protein Eng.Des.Sel., 29:135-147, 2016; PubMed: 26819240; DOI: 10.1093/protein/gzv067

実験手法

X-RAY DIFFRACTION (2.201 Å)