5D8T

RNA octamer containing (S)-5' methyl, 2'-F U.

Summary for 5D8T

• Entry DOI: 10.2210/pdb5d8t/pdb
• Descriptor: RNA oligonucleotide containing (S)-C5'-Me-2'-FU, COBALT HEXAMMINE(III) (3 entities in total)
• Functional Keywords: rna, modified base
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 5887.41

Authors

Harp, J.M.,Egli, M. (deposition date: 2015-08-17, release date: 2016-06-29, Last modification date: 2024-03-06)

• Primary citation: Kel In, A.V.,Zlatev, I.,Harp, J.,Jayaraman, M.,Bisbe, A.,O Shea, J.,Taneja, N.,Manoharan, R.M.,Khan, S.,Charisse, K.,Maier, M.A.,Egli, M.,Rajeev, K.G.,Manoharan, M.; Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.; J.Org.Chem., 81:2261-2279, 2016; PubMed: 26940174; DOI: 10.1021/acs.joc.5b02375

Experimental method

X-RAY DIFFRACTION (1.2 Å)