5D1Y
Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP
Summary for 5D1Y
Entry DOI | 10.2210/pdb5d1y/pdb |
Descriptor | Ribonucleoside-diphosphate reductase large subunit (1 entity in total) |
Functional Keywords | deoxyribonucleotide, oligomerization, atp cone, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 184700.78 |
Authors | Ando, N.,Li, H.,Brignole, E.J.,Thompson, S.,McLaughlin, M.I.,Page, J.,Asturias, F.,Stubbe, J.,Drennan, C.L. (deposition date: 2015-08-04, release date: 2016-01-20, Last modification date: 2023-09-27) |
Primary citation | Ando, N.,Li, H.,Brignole, E.J.,Thompson, S.,McLaughlin, M.I.,Page, J.E.,Asturias, F.J.,Stubbe, J.,Drennan, C.L. Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer. Biochemistry, 55:373-381, 2016 Cited by PubMed: 26727048DOI: 10.1021/acs.biochem.5b01207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (9.005 Å) |
Structure validation
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