5D0J
Grb7 SH2 with inhibitor peptide
Summary for 5D0J
Entry DOI | 10.2210/pdb5d0j/pdb |
Descriptor | Growth factor receptor-bound protein 7, G7-TEdFP peptide, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, sh2, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q14451 |
Total number of polymer chains | 6 |
Total formula weight | 56994.82 |
Authors | Gunzburg, M.J.,Watson, G.M.,Wilce, J.A.,Wilce, M.C.J. (deposition date: 2015-08-03, release date: 2016-06-15, Last modification date: 2023-09-27) |
Primary citation | Gunzburg, M.J.,Kulkarni, K.,Watson, G.M.,Ambaye, N.D.,Del Borgo, M.P.,Brandt, R.,Pero, S.C.,Perlmutter, P.,Wilce, M.C.,Wilce, J.A. Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6:27060-27060, 2016 Cited by PubMed: 27257138DOI: 10.1038/srep27060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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