5CWA

Structure of Anthranilate Synthase Component I (TrpE) from Mycobacterium tuberculosis with inhibitor bound

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5CWA の概要

• エントリーDOI: 10.2210/pdb5cwa/pdb
• 分子名称: Anthranilate synthase component 1, SULFATE ION, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: lyase, inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56110.76

構造登録者

Johnston, J.M.,Bashiri, G.,Evans, G.L.,Lott, J.S.,Baker, E.N. (登録日: 2015-07-28, 公開日: 2015-08-12, 最終更新日: 2023-09-27)

• 主引用文献: Bashiri, G.,Johnston, J.M.,Evans, G.L.,Bulloch, E.M.,Goldstone, D.C.,Jirgis, E.N.,Kleinboelting, S.,Castell, A.,Ramsay, R.J.,Manos-Turvey, A.,Payne, R.J.,Lott, J.S.,Baker, E.N.; Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.; Acta Crystallogr.,Sect.D, 71:2297-2308, 2015; PubMed: 26527146; DOI: 10.1107/S1399004715017216

実験手法

X-RAY DIFFRACTION (2.1 Å)