5CUU
Crystal structure of Trypanosoma cruzi Vacuolar Soluble Pyrophosphatases in complex with bisphosphonate inhibitor BPH-1260
Summary for 5CUU
Entry DOI | 10.2210/pdb5cuu/pdb |
Related | 5cuv 5cux 5cuy |
Descriptor | Acidocalcisomal pyrophosphatase, D-MALATE, 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium, ... (5 entities in total) |
Functional Keywords | substrate binding, acidocalcisomal pyrophosphatase, inhibitor, metal binding protein |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 2 |
Total formula weight | 96939.06 |
Authors | Liu, W.D.,Yang, Y.Y.,Ko, T.P.,Zheng, Y.Y.,Chen, C.C.,Guo, R.T. (deposition date: 2015-07-25, release date: 2016-03-02, Last modification date: 2023-11-08) |
Primary citation | Yang, Y.Y.,Ko, T.P.,Zheng, Y.Y.,Liu, W.D.,Chen, C.C.,Guo, R.T. Crystal structure of Trypanosoma cruzi protein in complex with ligand Acs Chem.Biol., 2016 |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
Download full validation report