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5CUQ

Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase

Summary for 5CUQ
Entry DOI10.2210/pdb5cuq/pdb
DescriptorNonstructural protein NS5, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA (3 entities in total)
Functional Keywordsinhibitor, complex, dengue virus, methyltransferase, viral protein-inhibitor complex, viral protein/inhibitor
Biological sourceDengue virus 3
Total number of polymer chains2
Total formula weight60884.02
Authors
Brecher, B.,Chen, H.,Li, Z.,Banavali, N.K.,Jones, S.A.,Zhang, J.,Kramer, L.D.,Li, H.M. (deposition date: 2015-07-24, release date: 2016-02-03, Last modification date: 2023-09-27)
Primary citationBrecher, M.,Chen, H.,Li, Z.,Banavali, N.K.,Jones, S.A.,Zhang, J.,Kramer, L.D.,Li, H.
Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.
Acs Infect Dis., 1:340-349, 2015
Cited by
PubMed: 26726314
DOI: 10.1021/acsinfecdis.5b00070
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.696 Å)
Structure validation

217705

건을2024-03-27부터공개중

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