5CU8

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)

Summary for 5CU8

• Entry DOI: 10.2210/pdb5cu8/pdb
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, 6-chloro-1,3-benzothiazol-2-amine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9UIF8
• Total number of polymer chains: 1
• Total formula weight: 13863.80

Authors

Bradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2015-07-24, release date: 2015-09-09, Last modification date: 2024-05-08)

• Primary citation: Bradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening); To be published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)