5CR7
Human cytosolic 5'-nucleotidase II in complex with N-(9H-Purin-6-yl)-3-(3-pyrrol-1-ylphenyl)benzamide
Summary for 5CR7
Entry DOI | 10.2210/pdb5cr7/pdb |
Related | 4H4B 5CQZ |
Descriptor | Cytosolic purine 5'-nucleotidase, ~{N}-(7~{H}-purin-6-yl)-3-(3-pyrrol-1-ylphenyl)benzamide, ACETATE ION, ... (7 entities in total) |
Functional Keywords | complex, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P49902 |
Total number of polymer chains | 2 |
Total formula weight | 130803.21 |
Authors | Aghajari, N.,Preeti, P. (deposition date: 2015-07-22, release date: 2016-01-13, Last modification date: 2024-01-10) |
Primary citation | Marton, Z.,Guillon, R.,Krimm, I.,Rahimova, R.,Egron, D.,Jordheim, L.P.,Aghajari, N.,Dumontet, C.,Perigaud, C.,Lionne, C.,Peyrottes, S.,Chaloin, L. Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach. J.Med.Chem., 58:9680-9696, 2015 Cited by PubMed: 26599519DOI: 10.1021/acs.jmedchem.5b01616 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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