5CR4

Crystal structure of the Sleeping Beauty transposase catalytic domain

Summary for 5CR4

Entry DOI	10.2210/pdb5cr4/pdb
Descriptor	Sleeping Beauty transposase, SB100X, SULFATE ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	transposase, tc1/mariner family, rnaseh fold, hydrolase
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	57174.98
Authors	Voigt, F.,Barabas, O. (deposition date: 2015-07-22, release date: 2016-03-30, Last modification date: 2024-01-10)
Primary citation	Voigt, F.,Wiedemann, L.,Zuliani, C.,Querques, I.,Sebe, A.,Mates, L.,Izsvak, Z.,Ivics, Z.,Barabas, O. Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering. Nat Commun, 7:11126-11126, 2016 Cited by PubMed: 27025571 DOI: 10.1038/ncomms11126 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation