5CQ6
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2,6-Pyridinedicarboxylic acid (SGC - Diamond I04-1 fragment screening)
Summary for 5CQ6
Entry DOI | 10.2210/pdb5cq6/pdb |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2B, 1,2-ETHANEDIOL, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9UIF8 |
Total number of polymer chains | 1 |
Total formula weight | 14515.50 |
Authors | Bradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2015-07-21, release date: 2015-09-09, Last modification date: 2024-05-08) |
Primary citation | Bradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2,6-Pyridinedicarboxylic acid (SGC - Diamond I04-1 fragment screening) To be published, |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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