Summary for 5CQ2
Entry DOI | 10.2210/pdb5cq2/pdb |
Descriptor | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, ligase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane: Q96J02 Cytoplasm : Q9H3M7 |
Total number of polymer chains | 3 |
Total formula weight | 13131.59 |
Authors | Liu, Y.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-07-21, release date: 2015-09-16, Last modification date: 2023-09-27) |
Primary citation | Liu, Y.,Lau, J.,Li, W.,Tempel, W.,Li, L.,Dong, A.,Narula, A.,Qin, S.,Min, J. Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem.J., 473:179-187, 2016 Cited by PubMed: 26527736DOI: 10.1042/BJ20150830 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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