5CMA
Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment
Summary for 5CMA
Entry DOI | 10.2210/pdb5cma/pdb |
Descriptor | Antibody ch8H9 Fab light chain, Antibody ch8H9 Fab heavy chain (3 entities in total) |
Functional Keywords | b7-h3 8h9 monoclonal antibody, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 46872.07 |
Authors | Ahmed, M.,Goldgur, Y.,Cheng, M.,Cheung, N.K. (deposition date: 2015-07-16, release date: 2015-10-28, Last modification date: 2023-09-27) |
Primary citation | Ahmed, M.,Cheng, M.,Zhao, Q.,Goldgur, Y.,Cheal, S.M.,Guo, H.F.,Larson, S.M.,Cheung, N.K. Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3. J.Biol.Chem., 290:30018-30029, 2015 Cited by PubMed: 26487718DOI: 10.1074/jbc.M115.679852 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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