5CMA

Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment

Summary for 5CMA

• Entry DOI: 10.2210/pdb5cma/pdb
• Descriptor: Antibody ch8H9 Fab light chain, Antibody ch8H9 Fab heavy chain (3 entities in total)
• Functional Keywords: b7-h3 8h9 monoclonal antibody, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 46872.07

Authors

Ahmed, M.,Goldgur, Y.,Cheng, M.,Cheung, N.K. (deposition date: 2015-07-16, release date: 2015-10-28, Last modification date: 2023-09-27)

• Primary citation: Ahmed, M.,Cheng, M.,Zhao, Q.,Goldgur, Y.,Cheal, S.M.,Guo, H.F.,Larson, S.M.,Cheung, N.K.; Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.; J.Biol.Chem., 290:30018-30029, 2015; PubMed: 26487718; DOI: 10.1074/jbc.M115.679852

Experimental method

X-RAY DIFFRACTION (2.5 Å)