5CI8
Crystal structure of human Tob in complex with inhibitor fragment 1
Summary for 5CI8
Entry DOI | 10.2210/pdb5ci8/pdb |
Related | 5CI9 |
Descriptor | Protein Tob1, pyrrolo[1,2-a]quinoxalin-4(5H)-one (2 entities in total) |
Functional Keywords | tob/btg family, inhibitor, complex, transcription-inhibitor complex, transcription/inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P50616 |
Total number of polymer chains | 1 |
Total formula weight | 38649.26 |
Authors | Bai, Y.,Tashiro, S.,Nagatoishi, S.,Suzuki, T.,Tsumoto, K.,Bartlam, M.,Yamamoto, T. (deposition date: 2015-07-11, release date: 2015-11-18, Last modification date: 2015-12-09) |
Primary citation | Bai, Y.,Tashiro, S.,Nagatoishi, S.,Suzuki, T.,Yan, D.,Liu, R.,Tsumoto, K.,Bartlam, M.,Yamamoto, T. Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach Protein Cell, 6:924-928, 2015 Cited by PubMed: 26518565DOI: 10.1007/s13238-015-0225-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.328 Å) |
Structure validation
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