5CGH

Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 5

Summary for 5CGH

Entry DOI	10.2210/pdb5cgh/pdb
Related	1RYP
Descriptor	Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (20 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor
Biological source	Saccharomyces cerevisiae S288C More
Cellular location	Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
Total number of polymer chains	30
Total formula weight	733058.84
Authors	Dubiella, C.,Groll, M. (deposition date: 2015-07-09, release date: 2015-12-02, Last modification date: 2024-06-26)
Primary citation	Dubiella, C.,Baur, R.,Cui, H.,Huber, E.M.,Groll, M. Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. Angew.Chem.Int.Ed.Engl., 54:15888-15891, 2015 Cited by PubMed: 26563572 DOI: 10.1002/anie.201506631 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation